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Journal of Clinical Microbiology, April 2007, p. 1315-1318, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.01688-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Systematic Survey of Nonspecific Agglutination by Candida spp. in Latex Assays{triangledown}

Karsten Becker,1,2* Ahmed S. Almasri,1 Christof von Eiff,1,2 Georg Peters,1,2 Christine Heilmann,1,2 and Wolfgang Fegeler1

Institute of Medical Microbiology,1 Interdisciplinary Centre of Clinical Research (IZKF), Münster, University Hospital of Münster, 48149 Münster, Germany2

Received 16 August 2006/ Returned for modification 3 January 2007/ Accepted 21 January 2007

In order to demonstrate that cells of Candida spp. may show considerable nonspecific agglutination in latex agglutination tests, 150 clinical and reference isolates of 12 yeast species were systematically studied by applying various test parameters. In fact, 40 (26.7%) of these isolates revealed nonspecific results, significantly associated with the time allowed for agglutination.

* Corresponding author. Mailing address: Institute of Medical Microbiology, University of Münster, D-48149 Münster, Germany. Phone: (49) 251 83-55375. Fax: (49) 251 83-55350. E-mail: kbecker{at}uni-muenster.de

{triangledown} Published ahead of print on 31 January 2007.

Journal of Clinical Microbiology, April 2007, p. 1315-1318, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.01688-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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