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Journal of Clinical Microbiology, April 2007, p. 1350-1352, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.02274-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

High Frequencies of Clindamycin and Tetracycline Resistance in Methicillin-Resistant Staphylococcus aureus Pulsed-Field Type USA300 Isolates Collected at a Boston Ambulatory Health Center{triangledown}

Linda L. Han,1* Linda K. McDougal,2 Rachel J. Gorwitz,2 Kenneth H. Mayer,3,4 Jean B. Patel,2 Janet M. Sennott,1 and John L. Fontana1

Massachusetts Department of Public Health, State Laboratory Institute, Jamaica Plain, Massachusetts 02130,1 Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333,2 Fenway Community Health Center, Boston, Massachusetts 02115,3 Brown University/Miriam Hospital, Providence, Rhode Island 029064

Received 8 November 2006/ Returned for modification 5 January 2007/ Accepted 29 January 2007

Individual or multiple resistance to clindamycin, tetracycline, erythromycin, levofloxacin, or mupirocin was detected in a large proportion of methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at an ambulatory health center in Boston. The clindamycin, tetracycline, and mupirocin resistance genes identified in these isolates are commonly associated with plasmids.

* Corresponding author. Mailing address: State Laboratory Institute, 305 South St., Jamaica Plain, MA 02130. Phone: (617) 983-4362. Fax: (617) 983-6618. E-mail: linda.han{at}state.ma.us

{triangledown} Published ahead of print on 7 February 2007.

Journal of Clinical Microbiology, April 2007, p. 1350-1352, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.02274-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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