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Journal of Clinical Microbiology, May 2007, p. 1634-1636, Vol. 45, No. 5
0095-1137/07/$08.00+0     doi:10.1128/JCM.00122-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Variation in the Number of Tandem Repeats and Profile of Surface Protein Genes among Invasive Group B Streptococci Correlates with Patient Age{triangledown}

Yueh-Ren Ho,1,7 Chien-Ming Li,2 Hsin-Pi Su,3 Jane-Hong Wu,5 Yu-Ching Tseng,4 Yuh-Jyh Lin,6 and Jiunn-Jong Wu4,7*

Departments of Biochemistry and Molecular Biology,1 Medical Laboratory Science and Biotechnology,4 Microbiology and Immunology,5 Pediatrics,6 Institute of Basic Medical Sciences,7 College of Medicine, National Cheng Kung University, Tainan, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan,2 Laboratory for Bacteriology and Mycology, Center for Research and Diagnostics, Center for Disease Control, Taipei, Taiwan3

Received 17 January 2007/ Returned for modification 19 February 2007/ Accepted 27 February 2007

The average number of tandem repeats of the rib gene (which encodes the Rib surface protein) in invasive group B streptococci from 29 neonates was smaller than that from 20 adults (6.8 and 8.6, respectively; P < 0.05), implying a distinct contribution of immunity toward this age-related variation.

* Corresponding author. Mailing address: Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, No. 1 University Road, Tainan 701, Taiwan. Phone: 886-6-2353535, ext. 5605. Fax: 886-6-2363956. E-mail: jjwu{at}mail.ncku.edu.tw

{triangledown} Published ahead of print on 7 March 2007.

Journal of Clinical Microbiology, May 2007, p. 1634-1636, Vol. 45, No. 5
0095-1137/07/$08.00+0     doi:10.1128/JCM.00122-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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