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Journal of Clinical Microbiology, June 2007, p. 1981-1984, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00273-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Epidemiologic Distribution of the Arginine Catabolic Mobile Element among Selected Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates{triangledown}

Richard V. Goering,1* Linda K. McDougal,2 Greg E. Fosheim,2 Kristin K. Bonnstetter,1 Daniel J. Wolter,1 and Fred C. Tenover2

Creighton University School of Medicine, Omaha, Nebraska, 68178,1 Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 303332

Received 2 February 2007/ Returned for modification 15 March 2007/ Accepted 27 March 2007

We tested 214 Staphylococcus aureus isolates for the arcA locus of the arginine catabolic mobile element (ACME). All USA300 SCCmec IVa isolates, but no isolates containing other SCCmec subtypes, were arcA positive. arcA was also detected in selected methicillin-susceptible USA300 and methicillin-resistant USA100 isolates. DNA sequence analysis confirmed the integration of ACME in orfX.

* Corresponding author. Mailing address: Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178. Phone: (402) 280-4098. Fax: (402) 280-1875. E-mail: rgoeri{at}creighton.edu

{triangledown} Published ahead of print on 4 April 2007.

Journal of Clinical Microbiology, June 2007, p. 1981-1984, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00273-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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