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Journal of Clinical Microbiology, June 2007, p. 2002-2004, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00104-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Molecular Epidemiology of the sil Streptococcal Invasive Locus in Group A Streptococci Causing Invasive Infections in French Children{triangledown}

Philippe Bidet, Céline Courroux, Christophe Salgueiro, Agnès Carol, Patricia Mariani-Kurkdjian, Stéphane Bonacorsi, and Edouard Bingen*

Université Paris VII, UFR Médicale; EA 3105, Laboratoire d'Études de Génétique Bactérienne dans les Infections de l'Enfant; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Microbiologie, Laboratoire associé au CNR des Streptocoques-Infections à Streptocoque du groupe A de l'Enfant, Hôpital Robert Debré, Paris, France

Received 15 January 2007/ Returned for modification 22 February 2007/ Accepted 12 March 2007

We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%), and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.

* Corresponding author. Mailing address: Service de Microbiologie, Hôpital Robert Debré, 48 Bd Sérurier, 75395 Paris cedex 19, France. Phone: 33 1 40 03 23 40. Fax: 33 1 40 03 24 50. E-mail: edouard.bingen{at}rdb.ap-hop-paris.fr

{triangledown} Published ahead of print on 21 March 2007.

Journal of Clinical Microbiology, June 2007, p. 2002-2004, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00104-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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