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Journal of Clinical Microbiology, June 2007, p. 2005-2008, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00578-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Evaluation of Moxalactam with the BD Phoenix System for Detection of Methicillin Resistance in Coagulase-Negative Staphylococci{triangledown}

H. Pupin,1 H. Renaudin,1 O. Join-Lambert,2 C. Bébéar,1 F. Mégraud,1 and P. Lehours1*

CHU de Bordeaux, Hôpital Pellegrin, Laboratoire de Bactériologie, Place Amélie Raba Léon, 33076 Bordeaux, France,1 Hôpital Necker Enfants Malades, Service de Microbiologie, 149 rue de Sèvres, 75015 Paris, France2

Received 15 March 2007/ Returned for modification 22 March 2007/ Accepted 3 April 2007

The performance of moxalactam with the BD Phoenix system for the detection of methicillin resistance in coagulase-negative staphylococci was evaluated by use of a collection of 186 strains. Moxalactam was a better drug as an indicator of methicillin resistance for mecA-positive strains than oxacillin and cefoxitin were. For strains other than Staphylococcus saprophyticus, a moxalactam MIC >16 µg/ml was indicative of methicillin resistance.

* Corresponding author. Mailing address: Laboratoire de Bactériologie, CHU Pellegrin, Place Amélie Raba Léon, 33076 Bordeaux cedex, France. Phone: 33 5 57 57 12 86. Fax: 33 5 56 51 41 82. E-mail: philippe.lehours{at}chu-bordeaux.fr

{triangledown} Published ahead of print on 11 April 2007.

Journal of Clinical Microbiology, June 2007, p. 2005-2008, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00578-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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