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Journal of Clinical Microbiology, June 2007, p. 2017-2019, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.02566-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Genetic Relatedness of Streptococcus pneumoniae Isolates from Paired Blood and Respiratory Specimens{triangledown}

L. J. Harrell,2,3,4* S. K. Sharps,4,{dagger} R. A. Bean,4 and L. B. Reller1,3,4

Departments of Medicine,1 Molecular Genetics and Microbiology,2 Pathology, Duke University School of Medicine,3 Clinical Microbiology Laboratory, Duke University Health System, Durham, North Carolina4

Received 21 December 2006/ Accepted 2 April 2007

To assess the relatedness of Streptococcus pneumoniae isolates recovered concurrently from blood and respiratory tract specimens from patients with pneumonia, we analyzed 24 paired isolates by pulsed-field gel electrophoresis (PFGE), serotyping, and antimicrobial susceptibility testing. PFGE, serotype, and/or susceptibility patterns were identical for 22 of 24 pairs. Susceptibility results for blood isolates should guide therapy.

* Corresponding author. Mailing address: Clinical Microbiology Laboratory, Duke University Medical Center, Box 3879, Room 116, CARL Building, Research Drive, Durham, NC 27710. Phone: (919) 684-2807. Fax: (919) 684-8519. E-mail: lizzie.harrell{at}duke.edu

{triangledown} Published ahead of print on 11 April 2007.

{dagger} Present address: Department of Medicine, University of Pennsylvania, Philadelphia, PA.

Journal of Clinical Microbiology, June 2007, p. 2017-2019, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.02566-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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