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Journal of Clinical Microbiology, June 2007, p. 2068-2071, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00320-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Fatal Echovirus 18 Leukoencephalitis in a Child{triangledown}

Delphine Brunel,1,3 Jérôme Jacques,1,2 Jacques Motte,4 and Laurent Andréoletti1,2*

Laboratoire de Virologie, Centre Hospitalier Universitaire,1 IFR 53/EA-3798 (DAT /PPCIDH), Faculté de Médecine,2 Service de Pédiatrie A, American Memorial Hospital, Centre Hospitalier Universitaire,3 INSERM Unité 666, Strasbourg, France4

Received 9 February 2007/ Returned for modification 1 April 2007/ Accepted 7 April 2007

Rare cases of leukoencephalitis have been reported in infants with documented enterovirus (EV) central nervous system (CNS) infections. A case of fatal encephalitis with white matter lesions caused by echovirus 18 is described, and it highlights the role of EV CNS infection as a potential cause of leukoencephalitis in infants.

* Corresponding author. Mailing address: Laboratoire de Virologie, Service de Microbiologie, Hôpital Robert Debré, Avenue du Général Koenig, 51092, Reims Cedex, France. Phone: (33) 3 26 78 39 93. Fax: (33) 3 26 78 41 34. E-mail: landreoletti{at}chu-reims.fr

{triangledown} Published ahead of print on 18 April 2007.

Journal of Clinical Microbiology, June 2007, p. 2068-2071, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00320-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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Copyright © 2007 by the American Society for Microbiology. All rights reserved.