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Journal of Clinical Microbiology, August 2007, p. 2684-2685, Vol. 45, No. 8
0095-1137/07/$08.00+0     doi:10.1128/JCM.02457-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Characterization of a Catalase-Negative Methicillin-Resistant Staphylococcus aureus Strain{triangledown}

B. M. Grüner,1,{dagger} S.-R. Han,1*,{dagger} H.-G. Meyer,2 U. Wulf,1 S. Bhakdi,1 and E. K. Siegel1

Institute of Medical Microbiology, Johannes Gutenberg University, D-55101 Mainz,1 Department of Health and Infection Prevention, Rheinland-Pfalz Center for Laboratory Investigation, D-56068 Koblenz, Germany2

Received 7 December 2006/ Returned for modification 21 February 2007/ Accepted 11 June 2007

We describe an unusual clinical strain of catalase-negative methicillin-resistant Staphylococcus aureus sensu stricto. Sequence analysis of its catalase gene showed 99.60% identities to the catalase genes of the reference strains. A 5-base deletion, however, led to a shift of the nucleotide reading frame and a loss of the enzymatic activity.


* Corresponding author. Mailing address: Institute of Medical Microbiology, Johannes Gutenberg University, Hochhaus am Augustusplatz, D-55101 Mainz, Germany. Phone: (49) 6131 3937341. Fax: (49) 6131 3932359. E-mail: srhan{at}uni-mainz.de

{triangledown} Published ahead of print on 20 June 2007.

{dagger} B. M. Grüner and S.-R. Han contributed equally to the paper.


Journal of Clinical Microbiology, August 2007, p. 2684-2685, Vol. 45, No. 8
0095-1137/07/$08.00+0     doi:10.1128/JCM.02457-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




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