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Journal of Clinical Microbiology, August 2007, p. 2701-2703, Vol. 45, No. 8
0095-1137/07/$08.00+0     doi:10.1128/JCM.00642-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Nonsporulating Clinical Isolate Identified as Petromyces alliaceus (Anamorph Aspergillus alliaceus) by Morphological and Sequence-Based Methods{triangledown}

S. Arunmozhi Balajee,1* Mark D. Lindsley,1 Naureen Iqbal,1 James Ito,2 Peter G. Pappas,3 and Mary E. Brandt1

Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia,1 City of Hope National Medical Center, Duarte, California,2 Division of Infectious Diseases, University of Alabama at Birmingham, Alabama3

Received 22 March 2007/ Returned for modification 3 May 2007/ Accepted 22 May 2007

Concerted morphological and sequencing-based strategies revealed the identity of a nonsporulating clinical isolate as Petromyces alliaceus (anamorph Aspergillus alliaceus). This rare Aspergillus sp. was recovered as the etiological agent of invasive pulmonary aspergillosis and had reduced in vitro susceptibilities to amphotericin B and caspofungin, which correlated with clinical failure of therapy.

* Corresponding author. Mailing address: Mycotic Diseases Branch, Centers for Disease Control and Prevention, Mail Stop-G 11, 1600 Clifton Road, Atlanta, GA 30333. Phone: (404) 639-3337. Fax: (404) 639-3546. E-mail: fir3{at}cdc.gov

{triangledown} Published ahead of print on 30 May 2007.

Journal of Clinical Microbiology, August 2007, p. 2701-2703, Vol. 45, No. 8
0095-1137/07/$08.00+0     doi:10.1128/JCM.00642-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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