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Journal of Clinical Microbiology, September 2007, p. 3086-3088, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00593-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

First Contemporary Case of Human Infection with Cryptococcus gattii in Puget Sound: Evidence for Spread of the Vancouver Island Outbreak{triangledown}

Arlo Upton,1 James A. Fraser,2,3 Sarah E. Kidd,4 Camille Bretz,1 Karen H. Bartlett,4 Joseph Heitman,3 and Kieren A. Marr1,5*

Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, Washington,1 University of Queensland, Molecular and Microbial Sciences, Brisbane, Australia,2 Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina,3 School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC V6T 1Z3, Canada,4 Department of Medicine, Oregon Health and Science University, Portland, Oregon5

Received 17 March 2007/ Returned for modification 2 June 2007/ Accepted 13 June 2007

We report a case of cryptococcosis due to C. gattii which appears to have been acquired in the Puget Sound region, Washington State. Genotyping confirmed identity to the predominant Vancouver Island genotype. This is the first documented case of human disease by the major Vancouver Island emergence strain acquired within the United States.

* Corresponding author. Mailing address: Oregon Health and Science University, Division of Infectious Diseases, 3181 SW Sam Jackson Park Rd., Portland, OR 97239. Phone: (503) 418-1685. Fax: (503) 494-4264. E-mail: marrki{at}ohsu.edu

{triangledown} Published ahead of print on 27 June 2007.

Journal of Clinical Microbiology, September 2007, p. 3086-3088, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00593-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Mershon, K. L., Vasuthasawat, A., Lawson, G. W., Morrison, S. L., Beenhouwer, D. O. (2009). Role of Complement in Protection against Cryptococcus gattii Infection. Infect. Immun. 77: 1061-1070 [Abstract] [Full Text]  
  • Byrnes, E. J. III, Bildfell, R. J., Dearing, P. L., Valentine, B. A., Heitman, J. (2009). Cryptococcus gattii with bimorphic colony types in a dog in western Oregon: additional evidence for expansion of the Vancouver Island outbreak. jvdi 21: 133-136 [Abstract] [Full Text]  
  • Chaskes, S., Frases, S., Cammer, M., Gerfen, G., Casadevall, A. (2008). Growth and Pigment Production on D-Tryptophan Medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans. J. Clin. Microbiol. 46: 255-264 [Abstract] [Full Text]  


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