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Journal of Clinical Microbiology, September 2007, p. 3101-3104, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00656-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Impact of the COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5, on Clinical Laboratory Operations{triangledown}

Jeffrey J. Germer,1 Jordan L. Bendel,1 Craig A. Dolenc,1 Sarah R. Nelson,1 Amanda L. Masters,1 Tara M. Gerads,1 Jayawant N. Mandrekar,2 P. Shawn Mitchell,1 and Joseph D. C. Yao1*

Division of Clinical Microbiology,1 Section of Biostatistics, Mayo Clinic, Rochester, Minnesota2

Received 23 March 2007/ Returned for modification 10 June 2007/ Accepted 5 July 2007

The COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5 (CAP/CA), and the COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5, were compared. CAP/CA reduced and consolidated labor while modestly increasing assay throughput without increased failure rates or direct costs, regardless of batch size and assay format.


* Corresponding author. Mailing address: Division of Clinical Microbiology, Mayo Clinic, Su 1-602, 200 First Street SW, Rochester, MN 55905. Phone: (507) 266-4811. Fax: (507) 266-4341. E-mail: jdcyao{at}mayo.edu

{triangledown} Published ahead of print on 18 July 2007.


Journal of Clinical Microbiology, September 2007, p. 3101-3104, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00656-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.