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Journal of Clinical Microbiology, September 2007, p. 3111-3114, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00590-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Implementation Validation Performed in Rwanda To Determine Whether the INNO-LiPA Rif.TB Line Probe Assay Can Be Used for Detection of Multidrug-Resistant Mycobacterium tuberculosis in Low-Resource Countries{triangledown}

Cindy Maria Quezada,1 Eliane Kamanzi,2 Julienne Mukamutara,3 Pim De Rijk,4 Leen Rigouts,4 Françoise Portaels,4 and Yanis Ben Amor5*

Laboratory of Structural Microbiology, Rockefeller University,1 Earth Institute, Columbia University, New York, New York,5 National Reference Laboratory, Kigali,2 University Hospital Butare, Butare, Rwanda,3 Mycobacteriology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium4

Received 16 March 2007/ Returned for modification 9 May 2007/ Accepted 2 July 2007

We validated the implementation of the INNO-LiPA Rif.TB line probe assay, a diagnostic test for rapid detection of multidrug-resistant tuberculosis (MDR-TB), in Rwanda. No substantial difference was found between results obtained in Rwanda and results obtained in Belgium with the same samples. This rapid diagnostic test for MDR-TB can therefore be reliably implemented in a resource-poor setting.

* Corresponding author. Mailing address: Earth Institute, Columbia University, Hogan Hall B-19, Mail Code 3277, 2910 Broadway, New York, NY 10025. Phone: (212) 854-0497. Fax: (212) 854-0274. E-mail: yba2101{at}columbia.edu

{triangledown} Published ahead of print on 11 July 2007.

Journal of Clinical Microbiology, September 2007, p. 3111-3114, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.00590-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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