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Journal of Clinical Microbiology, September 2007, p. 3125-3126, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.01169-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Prosthetic Valve Endocarditis Caused by Streptobacillus moniliformis: a Case of Rat Bite Fever{triangledown}

Po-Lin Chen,1,6* Nan-Yao Lee,1 Jing-Jou Yan,2,4 Yu-jen Yang,3,4 Hung-Mo Chen,2 Chia-Ming Chang,1 Hsin-Chun Lee,1,4,6 Nai-Ying Ko,5 Chao-Han Lai,3 and Wen-Chien Ko1,4

Departments of Internal Medicine,1 Pathology,2 Surgery, National Cheng Kung University Hospital,3 Departments of Medicine,4 Nursing,5 Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan6

Received 11 June 2007/ Returned for modification 25 June 2007/ Accepted 17 July 2007

We report a case of rat bite fever caused by Streptobacillus moniliformis in Taiwan. It manifested as prosthetic valve endocarditis, which was cured by cardiac valve replacement and antimicrobial therapy. The DNA sequence of the 16S rRNA gene of S. moniliformis was detected in valve specimens by PCR and nucleotide sequencing.


* Corresponding author. Mailing address: Department of Internal Medicine, National Cheng Kung University Hospital, No. 138, Sheng Li Road, Tainan 704, Taiwan. Phone: 886-6-2353535, ext. 3596. Fax: 886-6-2752038. E-mail: winston{at}mail.ncku.edu.tw

{triangledown} Published ahead of print on 25 July 2007.


Journal of Clinical Microbiology, September 2007, p. 3125-3126, Vol. 45, No. 9
0095-1137/07/$08.00+0     doi:10.1128/JCM.01169-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.