JCM Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
JCM.01503-07v1
46/1/328    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fenner, L.
Right arrow Articles by Frei, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fenner, L.
Right arrow Articles by Frei, R.
Journal of Clinical Microbiology, January 2008, p. 328-330, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.01503-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Rapid and Reliable Diagnostic Algorithm for Detection of Clostridium difficile{triangledown}

Lukas Fenner,1 Andreas F. Widmer,2 Gisela Goy,1 Sonja Rudin,1 and Reno Frei1*

Microbiology Laboratory,1 Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland2

Received 26 July 2007/ Returned for modification 20 September 2007/ Accepted 2 November 2007

We evaluated a two-step algorithm for detection of Clostridium difficile in 1,468 stool specimens. First, specimens were screened by an immunoassay for C. difficile glutamate dehydrogenase antigen (C.DIFF CHEK-60). Second, screen-positive specimens underwent toxin testing by a rapid toxin A/B assay (TOX A/B QUIK CHEK); toxin-negative specimens were subjected to stool culture. This algorithm allowed final results for 92% of specimens with a turnaround time of 4 h.

* Corresponding author. Mailing address: Microbiology Laboratory, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland. Phone: 41 61 265 42 44. Fax: 41 61 265 53 55. E-mail: rfrei{at}uhbs.ch

{triangledown} Published ahead of print on 21 November 2007.

Journal of Clinical Microbiology, January 2008, p. 328-330, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.01503-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2008 by the American Society for Microbiology. All rights reserved.