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Journal of Clinical Microbiology, January 2008, p. 334-337, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.01618-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

High Rate of Human Bocavirus and Adenovirus Coinfection in Hospitalized Israeli Children{triangledown}

Musa Y. Hindiyeh,1* Nathan Keller,2 Michal Mandelboim,1 Daniela Ram,1 Jana Rubinov,1 Liora Regev,1 Virginia Levy,1 Sara Orzitzer,1 Hilda Shaharabani,1 Roberto Azar,1 Ella Mendelson,1,3,{dagger} and Zehava Grossman1,{dagger}

Central Virology Laboratory, Public Health Services, Ministry of Health, Sheba Medical Center, Tel-Hashomer, Israel,1 Department of Clinical Microbiology, Sheba Medical Center, Tel-Hashomer, Israel,2 Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel3

Received 14 August 2007/ Returned for modification 24 September 2007/ Accepted 17 October 2007

We investigated coinfection of human bocavirus (HBoV) and other respiratory viruses in hospitalized children by real-time PCR. A high rate (69.2%) of adenovirus infection was found among children infected with HBoV. Such high rates of HboV-adenovirus coinfection have not been previously reported, underscoring the need to investigate the contribution of HBoV in patient clinical presentations.

* Corresponding author. Mailing address: Central Virology Laboratory, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel. Phone: 972-3-530-2066. Fax: 972-3-530-2457. E-mail: hindiyeh{at}yahoo.com

{triangledown} Published ahead of print on 31 October 2007.

{dagger} E.M. and Z.G. contributed equally.

Journal of Clinical Microbiology, January 2008, p. 334-337, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.01618-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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