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Journal of Clinical Microbiology, October 2008, p. 3482-3483, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.00665-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Comparison of Two Rapid Human Immunodeficiency Virus (HIV) Assays, Determine HIV-1/2 and OraQuick Advance Rapid HIV-1/2, for Detection of Recent HIV Seroconversion{triangledown}

Rachana Kshatriya, Ada A. Cachafeiro, Ryan J. S. Kerr, Julie A. E. Nelson, and Susan A. Fiscus*

Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7290

Received 8 April 2008/ Returned for modification 3 June 2008/ Accepted 23 July 2008

Modified protocols of two rapid tests were compared with a less sensitive (LS) (detuned) enzyme immunoassay (EIA) for their abilities to distinguish recent human immunodeficiency virus (HIV) seroconversion from long-term infections. The results for samples from 100 HIV-positive patient that had previously been tested by the Vironostika LS EIA had a 97% concordance with the results of the Determine HIV 1/2 assay and 93% concordance with those of the OraQuick HIV 1/2 assay.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 79 Mary Ellen Jones, Box CB 7, Chapel Hill, NC 27599-7290. Phone: (919) 966-6872. Fax: (919) 966-9873. E-mail: fiscussa{at}med.unc.edu

{triangledown} Published ahead of print on 6 August 2008.

Journal of Clinical Microbiology, October 2008, p. 3482-3483, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.00665-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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