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Journal of Clinical Microbiology, October 2008, p. 3530-3533, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.01057-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Molecular Analysis of Varicella-Zoster Virus Strains Circulating in Tanzania Demonstrating the Presence of Genotype M1 {triangledown}

Jonas Schmidt-Chanasit,1* Stephan Ölschläger,1 Stephan Günther,1 Gerold Jaeger,2 Karoline Bleymehl,3 Susanne G. Schäd,4 Gerald Heckel,5 Rainer G. Ulrich,6 and Hans Wilhelm Doerr3

Bernhard-Nocht-Institute for Tropical Medicine, Diagnostic Virology Laboratory, D-20359 Hamburg, Germany,1 Ikonda Hospital, Makete District, Ikonda, Tanzania,2 Institute of Medical Virology, Hospital of the Johann Wolfgang Goethe University, D-60596 Frankfurt am Main, Germany,3 Department of Dermatology and Venereology, University of Rostock, D-18055 Rostock, Germany,4 Computational and Molecular Population Genetics Laboratory, Zoological Institute, University of Bern, CH-3012 Bern, Switzerland,5 Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute for Novel and Emerging Infectious Diseases, D-17493 Greifswald, Germany6

Received 4 June 2008/ Returned for modification 23 July 2008/ Accepted 6 August 2008

Based on analysis of 16,392 bp encompassing the complete open reading frames (ORFs) 1, 5, 31, 36, 37, 47, 60, 62, 67, and 68 of the genome of genotype M1 varicella-zoster virus (VZV) was found in swab samples originating from eight Tanzanian zoster patients. Moreover, sequence analysis suggests recombination events between different VZV genotypes within ORFs 1, 31, 60, and 67.

* Corresponding author. Mailing address: Bernhard-Nocht-Institute for Tropical Medicine, Diagnostic Virology Laboratory, Bernhard-Nocht-Strasse 74, D-20359 Hamburg, Germany. Phone: 49-40-42818-205. Fax: 49-40-42818-400. E-mail: jonassi{at}gmx.de

{triangledown} Published ahead of print on 13 August 2008.

Journal of Clinical Microbiology, October 2008, p. 3530-3533, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.01057-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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