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Journal of Clinical Microbiology, November 2008, p. 3850-3852, Vol. 46, No. 11
0095-1137/08/$08.00+0     doi:10.1128/JCM.01102-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Fatal Outcome of Hepatitis A Virus (HAV) Infection in a Traveler with Incomplete HAV Vaccination and Evidence of Rift Valley Fever Virus Infection{triangledown}

Anke Oltmann,1 Stephanie Kämper,2 Oliver Staeck,3 Jonas Schmidt-Chanasit,4 Stephan Günther,4 Thomas Berg,5 Christina Frank,6 Detlev H. Krüger,1 and Jörg Hofmann1*

Institute of Medical Virology, Helmut-Ruska-Haus,1 Department of Nephrology and Medical Intensive Care,2 Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine,3 Department of Hepatology and Gastroenterology, Charité University Medicine, Berlin, Germany,5 Department of Virology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany,4 Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany6

Received 10 June 2008/ Returned for modification 26 July 2008/ Accepted 21 August 2008

Hepatitis A virus (HAV) infection is rarely fatal except in patients with chronic liver disease. In the case reported here, an elderly women died of HAV infection 12 years after incomplete HAV vaccination. The possible role of a concordant Rift Valley fever virus infection acquired in Kenya is discussed.

* Corresponding author. Mailing address: Institute of Medical Virology, Berlin Charité University Medicine, Helmut-Ruska-Haus, Charitéplatz 1, 10117 Berlin, Germany. Phone: (0049) 30450525141. Fax: (0049) 30450525908. E-mail: joerg.hofmann{at}charite.de

{triangledown} Published ahead of print on 3 September 2008.

Journal of Clinical Microbiology, November 2008, p. 3850-3852, Vol. 46, No. 11
0095-1137/08/$08.00+0     doi:10.1128/JCM.01102-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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