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Journal of Clinical Microbiology, February 2008, p. 810-813, Vol. 46, No. 2
0095-1137/08/$08.00+0     doi:10.1128/JCM.01004-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Health Care-Associated Endocarditis Caused by Staphylococcus aureus with Reduced Susceptibility to Vancomycin{triangledown}

Chia-Yu Chi,1 Tsai-Ling Lauderdale,1 Shih-Min Wang,2 Jing-Ming Wu,3 Yu-Jen Yang,4 and Ching-Chuan Liu3*

Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan,1 Departments of Emergency Medicine,2 Pediatrics,3 Surgery, National Cheng Kung University and Hospital, Tainan, Taiwan4

Received 14 May 2007/ Returned for modification 10 October 2007/ Accepted 4 December 2007

Infective endocarditis (IE) caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility (SARV) has been reported worldwide. We report the successful treatment of a pediatric patient with SARV IE and characterization of the infecting strain. The MIC of vancomycin rose from 1.5 to 2 µg/ml, and the SARV was confirmed by population analysis.

* Corresponding author. Mailing address: Department of Pediatrics, National Cheng Kung University and Hospital, 138 Sheng-Li Road, Tainan 704, Taiwan. Phone: 886-6-2353535. Fax: 886-6-2753083. E-mail: liucc{at}mail.ncku.edu.tw

{triangledown} Published ahead of print on 12 December 2007.

Journal of Clinical Microbiology, February 2008, p. 810-813, Vol. 46, No. 2
0095-1137/08/$08.00+0     doi:10.1128/JCM.01004-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Sun, W., Chen, H., Liu, Y., Zhao, C., Nichols, W. W., Chen, M., Zhang, J., Ma, Y., Wang, H. (2009). Prevalence and Characterization of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Isolates from 14 Cities in China. Antimicrob. Agents Chemother. 53: 3642-3649 [Abstract] [Full Text]  


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