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Journal of Clinical Microbiology, March 2008, p. 1110-1112, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01974-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Dissemination of CTX-M-15 β-Lactamase Genes Carried on Inc FI and FII Plasmids among Clinical Isolates of Escherichia coli in a University Hospital in Istanbul, Turkey{triangledown}

Nevriye Gonullu,1* Zerrin Aktas,2 Cigdem Bal Kayacan,2 Melek Salcioglu,3 Alessandra Carattoli,4 Dong Eun Yong,5 and Timothy R. Walsh5

Department of Microbiology and Clinical Microbiology, Cerrahpasa Faculty of Medicine, University of Istanbul, Istanbul 34303, Turkey,1 Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, University of Istanbul, Istanbul 34300, Turkey,2 Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, University of Istanbul, Istanbul 34300, Turkey,3 Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanitá, 00161 Rome, Italy,4 Department of Medical Microbiology, School of Medicine, Heath Hospital, University of Cardiff, Cardiff CF14 4XN, United Kingdom5

Received 5 October 2007/ Returned for modification 12 November 2007/ Accepted 26 December 2007

The CTX-M-1 group was found in 86.8% of the Escherichia coli isolates from Istanbul. A subset study revealed all isolates carrying blaCTX-M-15 genes flanked by the insertion element ISEcp1. Plasmid typing of transconjugates carrying blaCTX-M-15 showed that most isolates belonged to the Inc/rep FII group but that one isolate also belonged to the FI group.

* Corresponding author. Mailing address: Department of Microbiology and Clinical Microbiology, Cerrahpasa Faculty of Medicine, University of Istanbul, Istanbul 34303, Turkey. Phone: 90 212 4143000. Fax: 90 212 6322122. E-mail: nevriegonullu{at}yahoo.com

{triangledown} Published ahead of print on 9 January 2008.

Journal of Clinical Microbiology, March 2008, p. 1110-1112, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01974-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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