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Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea,1 Microbiology and Immunology, The University of Western Australia, Perth, Western Australia,2 Department of Laboratory Medicine, Chungnam National University, College of Medicine, Daejeon, Korea3
Received 13 June 2007/ Returned for modification 20 August 2007/ Accepted 8 January 2008
Of 462 Korean Clostridium difficile isolates, 77.5% were toxin B positive but 21.4% were toxin A negative (A– B+). The binary toxin gene was detected in nine isolates. A higher fluoroquinolone resistance of A– B+ strains may contribute to the increase of these strains. Toxin A detection alone may underdiagnose C. difficile-associated disease.
Published ahead of print on 16 January 2008.
| Antimicrob. Agents Chemother. | Clin. Microbiol. Rev. |
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| Clin. Vaccine Immunol. | ALL ASM JOURNALS |
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