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Journal of Clinical Microbiology, March 2008, p. 1144-1147, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.02029-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Severe Necrotizing Fasciitis in a Human Immunodeficiency Virus-Positive Patient Caused by Methicillin-Resistant Staphylococcus aureus{triangledown}

Randall J. Olsen,1 Kevin M. Burns,1 Liang Chen,2 Barry N. Kreiswirth,2 and James M. Musser1*

Clinical Microbiology Laboratory, Department of Pathology and Laboratory Medicine, The Methodist Hospital, and Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas 77030,1 The Public Health Research Institute Tuberculosis Center at the International Center for Public Health, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 071032

Received 17 October 2007/ Returned for modification 26 November 2007/ Accepted 8 January 2008

Methicillin-resistant Staphylococcus aureus (MRSA) is a rarely reported cause of necrotizing fasciitis. We report an unusually severe case of MRSA necrotizing fasciitis in a previously undiagnosed AIDS patient. Molecular analysis revealed that the strain had the USA300/spa1 genotype, now an abundant cause of community-acquired MRSA infection.

* Corresponding author. Mailing address: Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, 6565 Fannin Street, B490, Houston, TX 77030. Phone: (713) 441-5890. Fax: (713) 441-3447. E-mail: jmmusser{at}tmhs.org

{triangledown} Published ahead of print on 16 January 2008.

Journal of Clinical Microbiology, March 2008, p. 1144-1147, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.02029-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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