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Journal of Clinical Microbiology, April 2008, p. 1526-1529, Vol. 46, No. 4
0095-1137/08/$08.00+0     doi:10.1128/JCM.02188-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Genetic Features of Clinical Isolates of Streptococcus dysgalactiae subsp. equisimilis Possessing Lancefield's Group A Antigen{triangledown}

Daisuke Tanaka,1* Junko Isobe,1 Masanori Watahiki,1 Yoshiyuki Nagai,1 Chihiro Katsukawa,2 Ryuji Kawahara,2 Miyoko Endoh,3 Rumi Okuno,3 Nanako Kumagai,4 Masakado Matsumoto,5 Yoshiro Morikawa,6 Tadayoshi Ikebe,7 Haruo Watanabe,7 and the Working Group for Group A Streptococci in Japan,{dagger}

Department of Bacteriology, Toyama Institute of Health, Toyama,1 Department of Infectious Diseases, Osaka Prefectural Institute of Public Health, Osaka,2 Department of Bacteriology, Tokyo Metropolitan Institute of Public Health, Tokyo,3 Department of Microbiology, Fukushima Institute of Public Health, Fukushima,4 Department of Microbiology, Aichi Prefectural Institute of Public Health, Aichi,5 Morikawa Pediatric Clinic, Osaka,6 Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan7

Received 13 November 2007/ Returned for modification 19 December 2007/ Accepted 19 February 2008

Thirteen Streptococcus dysgalactiae subsp. equisimilis isolates possessing Lancefield's group A antigen recovered from people in Japan during 2000 to 2004 were genotyped. The results indicate that a conserved clone has persisted and spread within Japan, and two different emm types were observed within members of this clone.

* Corresponding author. Present address: Graduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama 930-8555, Japan. Phone: 81-76-445-6673. Fax: 81-76-445-6549. E-mail: tanakada{at}sci.u-toyama.ac.jp

{triangledown} Published ahead of print on 27 February 2008.

{dagger} The members of the Working Group for GAS in Japan are listed in Acknowledgments.

Journal of Clinical Microbiology, April 2008, p. 1526-1529, Vol. 46, No. 4
0095-1137/08/$08.00+0     doi:10.1128/JCM.02188-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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