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Journal of Clinical Microbiology, May 2008, p. 1818-1823, Vol. 46, No. 5
0095-1137/08/$08.00+0 doi:10.1128/JCM.02255-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
Characterization of New Staphylococcal Cassette Chromosome mec (SCCmec) and Topoisomerase Genes in Fluoroquinolone- and Methicillin-Resistant Staphylococcus pseudintermedius
Sybill Descloux,
Alexandra Rossano, and
Vincent Perreten*
Institute of Veterinary Bacteriology, University of Bern, CH-3001 Bern, Switzerland
Received 21 November 2007/
Returned for modification 13 January 2008/
Accepted 20 February 2008
Fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius isolates harbor two new staphylococcal cassette chromosome mec (SCCmec) elements that belong to class A, allotype 3 (SCCmec II-III), and to the new allotype 5 (SCCmec VII). Analysis of the complete nucleotide sequences of the topoisomerase loci gyrB/gyrA and grlB/grlA revealed mutations involved in fluoroquinolone resistance.
* Corresponding author. Mailing address: Institute of Veterinary Bacteriology, University of Bern, Länggass-Strasse 122, Postfach, CH-3001 Bern, Switzerland. Phone: 41 31 631 2430. Fax: 41 31 631 2634. E-mail:
vincent.perreten{at}vbi.unibe.ch
Published ahead of print on 27 February 2008.
Journal of Clinical Microbiology, May 2008, p. 1818-1823, Vol. 46, No. 5
0095-1137/08/$08.00+0 doi:10.1128/JCM.02255-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
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