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Journal of Clinical Microbiology, May 2008, p. 1832-1834, Vol. 46, No. 5
0095-1137/08/$08.00+0     doi:10.1128/JCM.00361-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Clinical Characteristics Associated with Isolation of Small-Colony Variants of Staphylococcus aureus and Pseudomonas aeruginosa from Respiratory Secretions of Patients with Cystic Fibrosis{triangledown}

Michael Schneider,1 Kathrin Mühlemann,1 Sara Droz,1 Sabine Couzinet,1 Carmen Casaulta,2 and Stefan Zimmerli1*

Institute for Infectious Diseases, University of Bern,1 Department of Pediatric Respiratory Medicine, University Hospital, Bern, Switzerland2

Received 22 February 2008/ Accepted 26 February 2008

During a 3-month period, small-colony variant phenotypes of both Staphylococcus aureus and Pseudomonas aeruginosa were isolated from respiratory secretions of 8.2% and 9.2%, respectively, of 98 patients with cystic fibrosis, particularly those with advanced pulmonary disease and prolonged antibiotic exposure.

* Corresponding author. Mailing address: Institute for Infectious Diseases, University of Bern, Friedbuehlstr. 51, P.O. Box 61, CH-3010 Bern, Switzerland. Phone: 41 31 632 32 58. Fax: 41 31 632 35 50. E-mail: stefan.zimmerli{at}ifik.unibe.ch

{triangledown} Published ahead of print on 5 March 2008.

Journal of Clinical Microbiology, May 2008, p. 1832-1834, Vol. 46, No. 5
0095-1137/08/$08.00+0     doi:10.1128/JCM.00361-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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