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Journal of Clinical Microbiology, June 2008, p. 2102-2105, Vol. 46, No. 6
0095-1137/08/$08.00+0     doi:10.1128/JCM.00363-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Sequence Type and emm Type Diversity in Streptococcus pyogenes Isolates Causing Invasive Disease in Norway between 1988 and 2003 {triangledown}

Roger Meisal,1,2 E. Arne Høiby,1 Ingeborg S. Aaberge,1 and Dominique A. Caugant1,2*

Department of Bacteriology and Immunology, Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway,1 Department of Oral Biology, University of Oslo, Oslo, Norway2

Received 22 February 2008/ Returned for modification 25 March 2008/ Accepted 4 April 2008

The incidence of invasive group A streptococcal disease has increased in Norway since the 1980s. Analysis of 100 isolates recovered from 1988 to 2003 showed an increased genotypic diversity over time, while the prevalence of the strain that dominated in 1988, sequence type (ST)-28/emm-1, decreased. Necrotizing fasciitis was often associated with ST-15/emm-3.

* Corresponding author. Mailing address: Department of Bacteriology and Immunology, Division of Infectious Disease Control, Norwegian Institute of Public Health, P.O. Box 4404, Nydalen, NO-0403 Oslo, Norway. Phone: 47 21 07 63 11. Fax: 47 21 07 65 18. E-mail: dominique.caugant{at}fhi.no

{triangledown} Published ahead of print on 16 April 2008.

Journal of Clinical Microbiology, June 2008, p. 2102-2105, Vol. 46, No. 6
0095-1137/08/$08.00+0     doi:10.1128/JCM.00363-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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