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Journal of Clinical Microbiology, June 2008, p. 2112-2114, Vol. 46, No. 6
0095-1137/08/$08.00+0     doi:10.1128/JCM.00156-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Identification of Factors Contributing to T-Cell Toxicity of Staphylococcus aureus Clinical Isolates

Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom,¹ Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom²

Received 25 January 2008/ Returned for modification 13 March 2008/ Accepted 4 April 2008

We examined the ability of 206 clinical isolates of Staphylococcus aureus to lyse T cells and found differences between Agr groups. We found that the beta and delta hemolysins are involved and that methicillin-resistant S. aureus strains are less toxic than methicillin-susceptible S. aureus strains.

Published ahead of print on 16 April 2008.