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Journal of Clinical Microbiology, July 2008, p. 2414-2417, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00369-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Comparison between Pernasal Flocked Swabs and Nasopharyngeal Aspirates for Detection of Common Respiratory Viruses in Samples from Children{triangledown}

Afaf Abu-Diab,1 Maysa Azzeh,2 Raed Ghneim,1 Riyad Ghneim,1 Madeleine Zoughbi,1 Sultan Turkuman,1 Nabeel Rishmawi,1 Abed-El-Razeq Issa,1 Issa Siriani,1 Rula Dauodi,1 Randa Kattan,1 and Musa Y. Hindiyeh1*

Caritas Baby Hospital, Bethlehem, Palestinian Authority Occupied,1 Al-Quds University, East Jerusalem, Palestinian Authority Occupied2

Received 23 February 2008/ Returned for modification 14 April 2008/ Accepted 5 May 2008

In this prospective study we compared the use of pernasal flocked swab samples with the use of nasopharyngeal aspirate (NPA) samples for the detection of respiratory viruses from 455 children less than 5 years of age. Overall, the sensitivity and the specificity of the pernasal flocked swab samples were 98.5% and 100%, respectively. The excellent sensitivity of the flocked swab samples in combination with the rapid means by which they may be collected makes them an alternative to NPA samples, whose collection is more invasive.

* Corresponding author. Mailing address: Clinical Laboratory Division, Caritas Baby Hospital, Bethlehem, Palestinian Authority Occupied. Phone: 972-2-275-8500. Fax: 972-2-275-8501. E-mail: Hindiyeh{at}yahoo.com

{triangledown} Published ahead of print on 14 May 2008.

Journal of Clinical Microbiology, July 2008, p. 2414-2417, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00369-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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