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Journal of Clinical Microbiology, July 2008, p. 2428-2431, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00698-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Isolation and Characterization of a Novel Francisella sp. from Human Cerebrospinal Fluid and Blood{triangledown}

Kiersten J. Kugeler,1 Paul S. Mead,1 Karin L. McGowan,2 Jon M. Burnham,2 Michael D. Hogarty,2 Eduardo Ruchelli,2 Kerry Pollard,3 Brigitte Husband,3 Caryn Conley,4 Tanya Rivera,4 Theodoros Kelesidis,5 Walter M. Lee,5 Walburga Mabey,5 Jonas M. Winchell,6 Heather L. Stang,6 J. Erin Staples,1 Linda J. Chalcraft,1 and Jeannine M. Petersen1*

Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado,1 Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania,2 Bureau of Laboratories, Pennsylvania Department of Health, Lionville, Pennsylvania,3 Massachusetts Department of Public Health State Laboratory Institute, Jamaica Plain, Massachusetts,4 Caritas St. Elizabeth's Medical Center, Boston, Massachusetts,5 Division of Bioterrorism Preparedness and Response, Centers for Disease Control and Prevention, Atlanta, Georgia6

Received 11 April 2008/ Accepted 5 May 2008

We describe the isolation of a Francisella sp. from normally sterile sites in acutely ill patients in two different states within 2 years. Microbiologic and molecular analyses indicate that this organism represents a novel Francisella sp. Clinicians and microbiologists should be aware of this new potential pathogen, as infection may be more common than recognized.

* Corresponding author. Mailing address: Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd., Fort Collins, CO 80521. Phone: (970) 266-3524. Fax: (970) 225-4257. E-mail: nzp0{at}cdc.gov

{triangledown} Published ahead of print on 21 May 2008.

Journal of Clinical Microbiology, July 2008, p. 2428-2431, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00698-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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