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Journal of Clinical Microbiology, September 2008, p. 3091-3093, Vol. 46, No. 9
0095-1137/08/$08.00+0     doi:10.1128/JCM.00712-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

VanB Phenotype-vanA Genotype Enterococcus faecium with Heterogeneous Expression of Teicoplanin Resistance{triangledown}

Il Joong Park,1 Wee Gyo Lee,1* Jong Hee Shin,2 Kyung Won Lee,3 and Gun Jo Woo4

Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea,1 Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea,2 Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea,3 Center for Food Safety Evaluation, Korea Food and Drug Administration, Seoul, Korea4

Received 14 April 2008/ Returned for modification 27 May 2008/ Accepted 23 June 2008

Six VanB phenotype-vanA genotype isolates of Enterococcus faecium with heterogeneous expression of teicoplanin resistance which gave rise to an outbreak at a Korean tertiary care teaching hospital have IS1216V in the coding region of vanS. This could be the underlying cause of the VanB phenotype-vanA genotype with heterogeneous expression of teicoplanin resistance.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Ajou University Hospital, San 5, Wonchun-Dong, Youngtong-Gu, Suwon 443-721, South Korea. Phone: 82-31-219-5785. Fax: 82-31-219-5778. E-mail: weegyo{at}ajou.ac.kr

{triangledown} Published ahead of print on 2 July 2008.

Journal of Clinical Microbiology, September 2008, p. 3091-3093, Vol. 46, No. 9
0095-1137/08/$08.00+0     doi:10.1128/JCM.00712-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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