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Journal of Clinical Microbiology, January 2009, p. 215-216, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01338-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Evaluation of the Rapid BioStar Optical Immunoassay for Detection of Chlamydia trachomatis in Adolescent Women{triangledown}

Claudiu I. Bandea,1 Emilia H. Koumans,2 Mary K. Sawyer,3 Jason Dover,1 Angelica O'Connor,2 John R. Papp,2 Elizabeth R. Unger,1 Jim Braxton,2 and Carolyn M. Black1*

National Center for Infectious Diseases,1 National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention,2 Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia3

Received 14 July 2008/ Returned for modification 2 September 2008/ Accepted 1 November 2008

We evaluated the performance of the BioStar Chlamydia OIA (optical immunoassay) in adolescent females (n = 261) from an inner city population. With a reference standard of two different nucleic acid amplification tests, the sensitivity and specificity of the BioStar Chlamydia OIA were 59.4 and 98.4%, respectively. Due to its relatively low sensitivity, the BioStar Chlamydia OIA should only be used in conjunction with more sensitive laboratory tests unless laboratory tests are unavailable or timely return for treatment is unlikely.


* Corresponding author. Mailing address: Centers for Disease Control and Prevention, MS C-17, 1600 Clifton Rd., Atlanta, GA 30333. Phone: (404) 639-3466. Fax: (404) 639-2155. E-mail: cblack{at}cdc.gov

{triangledown} Published ahead of print on 12 November 2008.


Journal of Clinical Microbiology, January 2009, p. 215-216, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01338-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Gaydos, C. A (2009). Can we climb out of the "pit" of poorly performing rapid diagnostic tests for chlamydia?. Sex. Transm. Infect. 85: 158-158 [Full Text]