This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kerr, R. J. S.
Right arrow Articles by Nelson, J. A. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kerr, R. J. S.
Right arrow Articles by Nelson, J. A. E.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, January 2009, p. 220-222, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01521-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Qualitative Human Immunodeficiency Virus RNA Analysis of Dried Blood Spots for Diagnosis of Infections in Infants{triangledown}

Ryan J. S. Kerr, Gray Player, Susan A. Fiscus, and Julie A. E. Nelson*

UNC Center for AIDS Research and Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599

Received 7 August 2008/ Returned for modification 10 October 2008/ Accepted 3 November 2008

The Gen-Probe Aptima human immunodeficiency virus type 1 (HIV-1) RNA assay was adapted for the diagnosis of HIV infection in infants by using dried blood spots. The assay was 99% sensitive (128/129) and 100% specific (162/162). This may prove useful in resource-limited settings, since it precludes the need for a phlebotomist and maintenance of a cold chain.

* Corresponding author. Mailing address: University of North Carolina at Chapel Hill, 11-141 Lineberger Cancer Center, CB 7295, Chapel Hill, NC 27599. Phone: (919) 843-9252. Fax: (919) 966-3015. E-mail: jnelson{at}med.unc.edu

{triangledown} Published ahead of print on 12 November 2008.

Journal of Clinical Microbiology, January 2009, p. 220-222, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01521-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»