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Journal of Clinical Microbiology, January 2009, p. 235-238, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01824-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Detection of Multiple Pathogenic Species in Saliva Is Associated with Periodontal Infection in Adults{triangledown}

Susanna Paju,1* Pirkko J. Pussinen,1 Liisa Suominen-Taipale,2 Mari Hyvönen,3 Matti Knuuttila,4 and Eija Könönen3,5

Institute of Dentistry, University of Helsinki and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki, Finland,1 Department of Health and Functional Capacity,2 Department of Bacterial and Inflammatory Diseases, National Public Health Institute (KTL), Helsinki, Finland,3 Institute of Dentistry, University of Oulu, Oulu, Finland,4 Institute of Dentistry, University of Turku, Turku, Finland5

Received 20 September 2008/ Returned for modification 1 November 2008/ Accepted 7 November 2008

We investigated whether certain bacterial species and their combinations in saliva can be used as markers for periodontitis. In 1,198 subjects, the detection of multiple species, rather than the presence of a certain pathogen, in saliva was associated with periodontitis as determined by the number of teeth with deepened periodontal pockets.

* Corresponding author. Mailing address: Institute of Dentistry, PL 41, FI-00014 University of Helsinki, Helsinki, Finland. Phone: 358-9-19127270. Fax: 358-9-19125194. E-mail: Susanna.Paju{at}helsinki.fi

{triangledown} Published ahead of print on 19 November 2008.

Journal of Clinical Microbiology, January 2009, p. 235-238, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01824-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Hyvarinen, K., Laitinen, S., Paju, S., Hakala, A., Suominen-Taipale, L., Skurnik, M., Kononen, E., Pussinen, P. J. (2009). Detection and quantification of five major periodontal pathogens by single copy gene-based real-time PCR. Innate Immunity 15: 195-204 [Abstract]  


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