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Journal of Clinical Microbiology, October 2009, p. 3350-3352, Vol. 47, No. 10
0095-1137/09/$08.00+0     doi:10.1128/JCM.00753-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Lysine Gingipain (kgp) Biovars of Porphyromonas gingivalis Exhibit Differential Distribution on Oral Mucosal Sites{triangledown}

Mangala A. Nadkarni,* Kim-Ly Chhour, Gina Browne, Nicholas A. Jacques, and Neil Hunter

Institute of Dental Research, Westmead Centre for Oral Health and Westmead Millennium Institute, Westmead, Australia

Received 15 April 2009/ Returned for modification 21 May 2009/ Accepted 3 August 2009

A predominant kgp biovar colonized subgingival sites and buccal and tongue mucosa in 45 of 56 adults in an isolated community. The presence of biovars 381, W83, and W83v, but not HG66, correlated with the Porphyromonas gingivalis load at diseased sites. Biovars W83 and W83v poorly colonized tongue and buccal mucosa.


* Corresponding author. Mailing address: Institute of Dental Research, Westmead Centre for Oral Health and Westmead Millennium Institute, P.O. Box 533, Wentworthville NSW 2145, Australia. Phone: 612-9845-7826. Fax: 612-9845-7599. E-mail: mangala_nadkarni{at}wmi.usyd.edu.au

{triangledown} Published ahead of print on 12 August 2009.


Journal of Clinical Microbiology, October 2009, p. 3350-3352, Vol. 47, No. 10
0095-1137/09/$08.00+0     doi:10.1128/JCM.00753-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.