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Journal of Clinical Microbiology, November 2009, p. 3726-3728, Vol. 47, No. 11
0095-1137/09/$08.00+0     doi:10.1128/JCM.00451-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Comparison of Three Reference Methods for Testing Susceptibility of Staphylococci to Trimethoprim-Sulfamethoxazole{triangledown}

R. Griffith,1* D. Creely,1 P. Revell,2 W. Michael Dunne,2 and D. Shortridge1

bioMérieux, Inc., Hazelwood, Missouri,1 Washington University School of Medicine, St. Louis, Missouri2

Received 3 March 2009/ Returned for modification 13 July 2009/ Accepted 1 September 2009

Three reference MIC methods approved by the Clinical and Laboratory Standards Institute were compared by testing 567 staphylococci against trimethoprim-sulfamethoxazole. Category agreement ranged from 94.9% (broth macrodilution versus broth microdilution) to 98.6% (agar dilution versus broth microdilution). Twenty-seven strains resistant by broth macrodilution were susceptible by broth microdilution.

* Corresponding author. Mailing address: bioMérieux, Inc., 595 Anglum Road, Hazelwood, MO 63042. Phone: (314) 731-7497. Fax: (314) 731-7454. E-mail: rita.griffith{at}na.biomerieux.com

{triangledown} Published ahead of print on 9 September 2009.

Journal of Clinical Microbiology, November 2009, p. 3726-3728, Vol. 47, No. 11
0095-1137/09/$08.00+0     doi:10.1128/JCM.00451-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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