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Journal of Clinical Microbiology, December 2009, p. 4150-4153, Vol. 47, No. 12
0095-1137/09/$08.00+0     doi:10.1128/JCM.00605-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Prevalence and Genotypes of Helicobacter pylori in Gastric Biopsy Specimens from Patients with Gastroduodenal Pathologies in the Cukurova Region of Turkey{triangledown}

Togrul Nagiyev,1* Erkan Yula,1 Bahri Abayli,2 and Fatih Koksal1

Department of Microbiology, Faculty of Medicine, University of Cukurova,1 Department of Gastroenterology, Adana Cukurova Governmental Hospital, Adana, Turkey2

Received 25 March 2009/ Returned for modification 29 May 2009/ Accepted 2 October 2009

The effects of Helicobacter pylori genotypes on clinical prognosis in the Cukurova region of Turkey were investigated by PCR. The prevalence of type I strains carrying the s1c allele, unlike in neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcers (P = 0.001), and that of type I strains carrying the s1a allele was found to be significantly higher in patients with duodenal ulcers (P < 0.001). The cagA gene was strongly associated with the more virulent vacA genotypes (P < 0.001).

* Corresponding author. Mailing address: Department of Microbiology, Faculty of Medicine, University of Cukurova, Adana, Turkey. Phone: 0090535 4108531. Fax: 0090322 3386539. E-mail: togrul_b{at}mynet.com

{triangledown} Published ahead of print on 21 October 2009.

Journal of Clinical Microbiology, December 2009, p. 4150-4153, Vol. 47, No. 12
0095-1137/09/$08.00+0     doi:10.1128/JCM.00605-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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