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Journal of Clinical Microbiology, February 2009, p. 477-480, Vol. 47, No. 2
0095-1137/09/$08.00+0     doi:10.1128/JCM.01663-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Rapid Emergence of emm84 among Invasive Streptococcus pyogenes Infections in Finland{triangledown}

Tuula Siljander,1* Outi Lyytikäinen,2 Susanna Vähäkuopus,1 Petrus Säilä,2,{dagger} Jari Jalava,3 and Jaana Vuopio-Varkila1

Hospital Bacteria Laboratory, Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Mannerheimintie 166, Helsinki FIN-00300, Finland,1 Department of Infectious Disease Epidemiology and Control, National Public Health Institute, Mannerheimintie 166, Helsinki FIN-00300, Finland,2 Microbial Ecology Laboratory, Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Kiinamyllynkatu 13, Turku FIN-20521, Finland3

Received 27 August 2008/ Returned for modification 19 October 2008/ Accepted 1 December 2008

From 2005 to 2007, in Finland, the incidence of invasive Streptococcus pyogenes disease increased sharply, partly due to the uncommon emm84 gene becoming more prevalent from 2006 onwards. The overall case fatality rate of infections caused by strains carrying emm84 was not significantly different than that of infections caused by other types (7% versus 10%, respectively; P = 0.50).

* Corresponding author. Present address: National Institute for Health and Welfare, P.O. Box 30, FIN-00271 Helsinki, Finland. Phone: 358 20 610 8558. Fax: 358 20 610 8238. E-mail: tuula.siljander{at}thl.fi

{triangledown} Published ahead of print on 10 December 2008.

{dagger} Present address: Department of Internal Medicine, Tampere University Hospital, P.O. Box 2000, Tampere FIN-33521, Finland.

Journal of Clinical Microbiology, February 2009, p. 477-480, Vol. 47, No. 2
0095-1137/09/$08.00+0     doi:10.1128/JCM.01663-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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