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Journal of Clinical Microbiology, February 2009, p. 496-498, Vol. 47, No. 2
0095-1137/09/$08.00+0     doi:10.1128/JCM.01429-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Severe Pneumonia with Leptotrichia sp. Detected Predominantly in Bronchoalveolar Lavage Fluid by Use of 16S rRNA Gene Sequencing Analysis{triangledown}

Toshinori Kawanami,1,2* Kazumasa Fukuda,2 Kazuhiro Yatera,1 Takashi Kido,1 Chiharu Yoshii,1 Hatsumi Taniguchi,2 and Masamitsu Kido1

Department of Respiratory Disease,1 Department of Microbiology, University of Occupational and Environmental Health, Japan, Fukuoka, Japan2

Received 25 July 2008/ Returned for modification 23 September 2008/ Accepted 22 November 2008

We present the first case of severe pneumonia possibly caused by Leptotrichia species with oral bacteria. This was found in a healthy but elderly subject whose bronchoalveolar lavage fluid was analyzed by 16S rRNA gene sequencing analysis. The combination of this method and microscopic observation provided useful information for diagnosis and treatment.

* Corresponding author. Mailing address: Department of Microbiology, School of Medicine, University of Occupational and Environmental Health, Japan (UOEH), 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu City, Fukuoka 807-8555, Japan. Phone: 81-93-691-7242. Fax: 81-93-602-4799. E-mail: namihei{at}med.uoeh-u.ac.jp

{triangledown} Published ahead of print on 3 December 2008.

Journal of Clinical Microbiology, February 2009, p. 496-498, Vol. 47, No. 2
0095-1137/09/$08.00+0     doi:10.1128/JCM.01429-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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