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Journal of Clinical Microbiology, March 2009, p. 833-836, Vol. 47, No. 3
0095-1137/09/$08.00+0     doi:10.1128/JCM.01464-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Evaluation of a Highly Sensitive Qualitative Human Immunodeficiency Virus Type 1 (HIV-1) RNA Assay for Detection of HIV-1 Suppression{triangledown}

C. Thomas Nugent,1* Vladislav Nodelman,1 Cristina Giachetti,1 Douglas D. Richman,2 and David J. Looney2

Gen-Probe, Incorporated, San Diego, California,1 VA San Diego Healthcare System and University of California, San Diego, San Diego, California2

Received 30 July 2008/ Returned for modification 10 October 2008/ Accepted 23 December 2008

By using a mathematical model, the APTIMA human immunodeficiency virus type 1 (HIV-1) RNA qualitative assay was evaluated as a semiquantitative assay to distinguish HIV-1 patient samples needing quantitation from samples in which the virus was suppressed with antiretroviral therapy.

* Corresponding author. Mailing address: Gen-Probe Inc., 10210 Genetic Center Dr., San Diego, CA 92121. Phone: (858) 410-8331. Fax: (858) 410-8302. E-mail: tomn{at}gen-probe.com

{triangledown} Published ahead of print on 30 December 2008.

Journal of Clinical Microbiology, March 2009, p. 833-836, Vol. 47, No. 3
0095-1137/09/$08.00+0     doi:10.1128/JCM.01464-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Stevens, W. S., Noble, L., Berrie, L., Sarang, S., Scott, L. E. (2009). Ultra-High-Throughput, Automated Nucleic Acid Detection of Human Immunodeficiency Virus (HIV) for Infant Infection Diagnosis Using the Gen-Probe Aptima HIV-1 Screening Assay. J. Clin. Microbiol. 47: 2465-2469 [Abstract] [Full Text]  


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