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Journal of Clinical Microbiology, April 2009, p. 1241-1243, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.01703-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Human Bocavirus in an Immunocompromised Child Presenting with Severe Diarrhea{triangledown}

Jutte J. C. de Vries,1,2* Robbert G. M. Bredius,3 Patrick F. van Rheenen,4 Frans J. W. Smiers,3 Elisabeth H. Schölvinck,4 Ann C. T. M. Vossen,2 Eric C. J. Claas,2 and Hubert G. M. Niesters1

Department of Medical Microbiology, Section Clinical Virology, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands,1 Department of Medical Microbiology, Section Clinical Virology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands,2 Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands,3 Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands4

Received 3 September 2008/ Returned for modification 9 January 2009/ Accepted 28 January 2009

Human bocavirus (HBoV) is frequently detected in young children with respiratory symptoms. However, the prevalence and pathogenicity of HBoV in immunocompromised patients are largely unknown. This report describes a case of life-threatening hypovolemic shock due to diarrhea associated with disseminated HBoV infection in an immunocompromised child.

* Corresponding author. Mailing address: Department of Medical Microbiology, Section Clinical Virology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Phone: 31 71 526 5242. Fax: 31 71 526 6981. E-mail: jjcdevries{at}lumc.nl

{triangledown} Published ahead of print on 4 February 2009.

Journal of Clinical Microbiology, April 2009, p. 1241-1243, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.01703-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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