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Journal of Clinical Microbiology, April 2009, p. 1255-1258, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.00849-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Growth of Adenocarcinoma on Routine Microbiological Media Inoculated with Fluid from a Pleural Effusion in an 82-Year-Old Female{triangledown}

Kenneth L. Muldrew1* and Stephen C. Edberg1,2,3,{dagger}

Departments of Internal Medicine,1 Laboratory Medicine,2 Chemical Engineering, School of Medicine, Yale University, New Haven, Connecticut3

Received 3 May 2008/ Returned for modification 17 June 2008/ Accepted 7 January 2009

We report the first documented case of adenocarcinoma cell growth on routine microbiological media. Pleural fluid culture from an 82-year-old female showed colonies with fried egg appearance on routine microbiological media that were negative for bacterial microorganisms. Stains of the colonies demonstrated clusters of viable neoplastic cells.

* Corresponding author. Mailing address: Clinical Microbiology Laboratory, CB-643, 20 York Street, New Haven, CT 06510. Phone: (203) 688-2457. Fax: (203) 688-4170. E-mail: kenneth.muldrew{at}yale.edu

{triangledown} Published ahead of print on 14 January 2009.

{dagger} Reprint requests. Mailing address: Clinical Microbiology Laboratory, CB-643, Department of Laboratory Medicine, Yale School of Medicine, 20 York Street, New Haven, CT 06510. Phone: (615) 429-6825. Fax: (203) 688-4170. E-mail: stephen.edberg{at}yale.edu.

Journal of Clinical Microbiology, April 2009, p. 1255-1258, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.00849-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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