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Journal of Clinical Microbiology, May 2009, p. 1568-1571, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.02040-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008 {triangledown}

Binh Minh Nguyen,1 Je Hee Lee,2,3 Ngo Tuan Cuong,1 Seon Young Choi,2,3 Nguyen Tran Hien,1 Dang Duc Anh,1 Hye Ri Lee,2 M. Ansaruzzaman,4 Hubert P. Endtz,4 Jongsik Chun,2,3 Anna Lena Lopez,2 Cecil Czerkinsky,2 John D. Clemens,2 and Dong Wook Kim2*

National Institute of Hygiene and Epidemiology, Hanoi, Vietnam,1 International Vaccine Institute, Seoul, Republic of Korea,2 School of Biological Sciences, Seoul National University, Seoul, Republic of Korea,3 International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh4

Received 21 October 2008/ Returned for modification 22 January 2009/ Accepted 5 March 2009

Vibrio cholerae O1 isolates collected during cholera outbreaks occurring from late 2007 to early 2008 in northern Vietnam were revealed to represent an altered strain containing the RS1 element followed by a CTX prophage harboring El Tor type rstR and classical ctxB on the large chromosome.

* Corresponding author. Mailing address: Laboratory Science Division, International Vaccine Institute, Seoul 151-919, Republic of Korea. Phone: 82-2-881-1402. Fax: 82-2-881-1410. E-mail: dwkim{at}ivi.int

{triangledown} Published ahead of print on 18 March 2009.

Journal of Clinical Microbiology, May 2009, p. 1568-1571, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.02040-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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