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Journal of Clinical Microbiology, June 2009, p. 1927-1930, Vol. 47, No. 6
0095-1137/09/$08.00+0     doi:10.1128/JCM.02070-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Reliability of the Vitek 2 Yeast Susceptibility Test for Detection of In Vitro Resistance to Fluconazole and Voriconazole in Clinical Isolates of Candida albicans and Candida glabrata{triangledown} ,{dagger}

Brunella Posteraro,1 Rosa Martucci,1 Marilena La Sorda,1 Barbara Fiori,1 Dominique Sanglard,2 Elena De Carolis,1 Ada Rita Florio,1 Giovanni Fadda,1 and Maurizio Sanguinetti1*

Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy,1 Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland2

Received 27 October 2008/ Returned for modification 15 January 2009/ Accepted 17 April 2009

The Vitek 2 yeast susceptibility test was evaluated by testing 122 Candida isolates against fluconazole and voriconazole. Excellent categorical agreement with the CLSI broth microdilution method was observed (97.5% for both the azoles). Moreover, the Vitek 2 system was able to identify all but 2 of 59 investigated fluconazole-resistant organisms.

* Corresponding author. Mailing address: Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Largo F. Vito, 1 00168 Rome, Italy. Phone: 39 06 30154964. Fax: 39 06 3051152. E-mail: msanguinetti{at}rm.unicatt.it

{triangledown} Published ahead of print on 29 April 2009.

{dagger} Supplemental material for this article may be found at http://jcm.asm.org/.

Journal of Clinical Microbiology, June 2009, p. 1927-1930, Vol. 47, No. 6
0095-1137/09/$08.00+0     doi:10.1128/JCM.02070-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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