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Journal of Clinical Microbiology, June 2009, p. 1969-1972, Vol. 47, No. 6
0095-1137/09/$08.00+0     doi:10.1128/JCM.02397-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Cutaneous Infection Caused by Macrophomina phaseolina in a Child with Acute Myeloid Leukemia{triangledown}

Ashok Srinivasan,1,3,6* Brian L. Wickes,4 Anna M. Romanelli,4 Larisa Debelenko,2 Jeffrey E. Rubnitz,1,6 Deanna A. Sutton,5 Elizabeth H. Thompson,5 Annette W. Fothergill,5 Michael G. Rinaldi,5 Randall T. Hayden,2 and Jerry L. Shenep3,6

Departments of Oncology,1 Pathology,2 Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee,3 Department of Microbiology and Immunology,4 Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas,5 Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee6

Received 14 December 2008/ Returned for modification 22 February 2009/ Accepted 9 April 2009

We report a case of Macrophomina phaseolina skin infection in an immunocompromised child with acute myeloid leukemia, which was treated successfully with posaconazole without recurrence after a hematopoietic stem cell transplant. The fungus was identified by DNA sequencing using both the internal transcribed spacer and D1/D2 region of the 28S ribosomal DNA gene.

* Corresponding author. Mailing address: Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 260, Memphis, TN 38105. Phone: (901) 595-4720. Fax: (901) 521-9005. E-mail: ashok.srinivasan{at}stjude.org

{triangledown} Published ahead of print on 22 April 2009.

Journal of Clinical Microbiology, June 2009, p. 1969-1972, Vol. 47, No. 6
0095-1137/09/$08.00+0     doi:10.1128/JCM.02397-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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