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Journal of Clinical Microbiology, July 2009, p. 2265-2268, Vol. 47, No. 7
0095-1137/09/$08.00+0     doi:10.1128/JCM.02012-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Prevalence and Molecular Diversity of Hepatitis B Virus and Hepatitis Delta Virus in Urban and Rural Populations in Northern Gabon in Central Africa{triangledown}

Maria Makuwa,1 Armel Mintsa-Ndong,1 Sandrine Souquière,1 Dieudonné Nkoghé,2 Eric M. Leroy,2 and Mirdad Kazanji1,3,4*

Unité de Virologie,1 Unité de Maladies Émergentes, Centre International de Recherches Médicales de Franceville (CIRMF), BP 769 Franceville, Gabon,2 Service de Coopération et d'Action Culturelle, French Embassy, BP 2105 Libreville, Gabon,3 Réseau International des Instituts Pasteur, Institut Pasteur, 28 rue du Dr Roux, Paris, France4

Received 17 October 2008/ Returned for modification 26 January 2009/ Accepted 5 May 2009

The prevalence of hepatitis B virus (HBV) surface antigen was significantly higher in urban (12.9%) than in rural (7.6%) populations (P = 0.003), but no difference was found in the prevalence of hepatitis delta virus (HDV), which was high in both populations. Phylogenetic analysis showed the circulation of HBV-A3 and -E genotypes and the presence of HDV-1, HDV-7, and HDV-8 clades.

* Corresponding author. Mailing address: Laboratoire de Rétrovirologie, CIRMF, BP 769 Franceville, Gabon. Phone: 241 06 63 66 61. Fax: 241 67 70 87. E-mail: m.kazanji{at}cirmf.org

{triangledown} Published ahead of print on 13 May 2009.

Journal of Clinical Microbiology, July 2009, p. 2265-2268, Vol. 47, No. 7
0095-1137/09/$08.00+0     doi:10.1128/JCM.02012-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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