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Journal of Clinical Microbiology, September 2009, p. 3011-3013, Vol. 47, No. 9
0095-1137/09/$08.00+0     doi:10.1128/JCM.00805-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Evaluation of the Cavidi ExaVir Load Assay (Version 3) for Plasma Human Immunodeficiency Virus Type 1 Load Monitoring{triangledown}

Vicki L. Greengrass,1 Megan M. Plate,1 Pauline M. Steele,1 Justin T. Denholm,2 Catherine L. Cherry,1,2,3 Lisa M. Morris,1 Anna Hearps,1 and Suzanne M. Crowe1,2,3*

Clinical Research Laboratory, Centre for Virology, Macfarlane Burnet Institute for Medical Research and Public Health, 85 Commercial Road, Melbourne, Australia,1 Infectious Diseases Unit, Alfred Hospital, Commercial Road, Melbourne, Australia,2 Department of Medicine, Monash University, 85 Commercial Road, Melbourne, Australia3

Received 20 April 2009/ Accepted 3 July 2009

We evaluated the new low-cost ExaVir Load (version 3) reverse transcriptase viral load assay against the Roche Cobas Amplicor assay. Results for samples tested using the reverse transcriptase assay correlated well with those obtained with the Roche assay (r = 0.85; n = 202). The version 3 reverse transcriptase assay shows improved sensitivity compared to the previous version.

* Corresponding author. Mailing address: Centre for Virology, Macfarlane Burnet Institute for Medical Research and Public Health, GPO Box 2284, Melbourne, Victoria 3001, Australia. Phone: 61 3 9282 2194. Fax: 61 3 9282 2142. E-mail: crowe{at}burnet.edu.au

{triangledown} Published ahead of print on 15 July 2009.

Journal of Clinical Microbiology, September 2009, p. 3011-3013, Vol. 47, No. 9
0095-1137/09/$08.00+0     doi:10.1128/JCM.00805-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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