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J Clin Microbiol. 1977 June; 5(6): 625-628

Electron capture gas chromatography detection and mass spectrum identification of 3-(2'-ketohexyl)indoline in spinal fluids of patients with tuberculous meningitis.

J B Brooks, G Choudhary, R B Craven, C C Alley, J A Liddle, D C Edman and J D Converse

ABSTRACT

A basic, extractable, indolic type of compound, which was derivatized with heptafluorobutyric anhydride and pyridine, was obtained from the cerebrospinal fluids of patients with acute tuberculous meningitis. The compound was detected by frequency-pulsed, modulated electron capture gas-liquid chromatography, and it was tentatively identified by mass spectrometry as 3-(2'-ketohexyl)indoline. The compound was found to be valuable for differentiating between tuberculous, cryptococcal, and aseptic meningitides.

J Clin Microbiol. 1977 June; 5(6): 625-628






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