JCM Accepts, published online ahead of print on 24 June 2009
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J. Clin. Microbiol. doi:10.1128/JCM.02351-08
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Comparative Evaluation of GenoType Mycobacteria Direct Assay with Gen-Probe Mycobacterium tuberculosis Amplified Direct Test and GenoType MTBDRplus for Direct Detection of Mycobacterium tuberculosis Complex in Clinical Samples

Ioannis K. Neonakis*, Zoe Gitti, Stavroula Baritaki, Efi Petinaki, Maria Baritaki, and Demetrios A. Spandidos

Mycobacteriology Laboratory, Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Heraklion, Greece; Department of Laboratory Medicine, School of Medicine, University of Crete, Heraklion, Greece; Department of Microbiology, School of Medicine, University of Thessaly, Larissa, Greece

* To whom correspondence should be addressed. Email: ineonakis{at}gmail.com.


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Abstract

Three molecular assays were evaluated for the direct detection of M. Tuberculosis complex in 125 respiratory and 22 non-respiratory samples. The overall sensitivities obtained were: GenoType MTBDRplus, 97.9%; GenoType Mycobacteria Direct, 93.7%; and Gen-Probe M. tuberculosis Amplified Direct Test, 89.6%. Specifity was 100% in the assays used.




This article has been cited by other articles:

  • Syre, H., Myneedu, V. P., Arora, V. K., Grewal, H. M. S. (2009). Direct Detection of Mycobacterial Species in Pulmonary Specimens by Two Rapid Amplification Tests, the Gen-Probe Amplified Mycobacterium tuberculosis Direct Test and the GenoType Mycobacteria Direct Test. J. Clin. Microbiol. 47: 3635-3639 [Abstract] [Full Text]  


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