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J Clin Microbiol. 1984 January; 19(1): 85-86

Comparison of the suitability of three common bacterial media for susceptibility testing of trimethoprim-sulfamethoxazole.

R W Ferguson and A S Weissfeld

ABSTRACT

The in vitro inhibitory activity of trimethoprim-sulfamethoxazole is inversely related to the amount of thymine and thymidine in the test medium; manufacturers must adequately control their media to avoid spurious antimicrobial susceptibility results. No differences were observed when commercial Mueller-Hinton broth and agar were compared with a semisynthetic broth medium by the use of microdilution and disk diffusion techniques.

J Clin Microbiol. 1984 January; 19(1): 85-86






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